SHP2/HDAC-IN-1 is a dual allosteric SHP2/HDAC inhibitor with IC 50 values of 20.4 nM ( SHP2 ) and 25.3 nM ( HDAC1 ) respectively. SHP2/HDAC-IN-1 triggers efficient antitumor immunity by activating T cells, enhancing the antigen presentation function and promoting cytokine secretion. SHP2/HDAC-IN-1 can be used in the research of cancer immunoresearch.
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