Romidepsin

Overview

Romidepsin (FK 228) is a Histone deacetylase ( HDAC ) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1 , HDAC2 , HDAC4 , and HDAC6 with IC 50 s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis .

Application

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Product Information

• Catalog No.: HY-15149
• CAS No.: 128517-07-7
• Molecular Formula: C24H36N4O6S2
• Molecular Weight: 540.70
• Purity: 99.98%
• Storage: Powder -20°C, 3 years * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.08 mg/mL (3.85 mM); Clear solution
• Availability: In-stock

Source

Original product source