PXS-4787 hydrochloride

Overview

PXS-4787 hydrochloride is a specific and effective pan- LOX ( lysyl oxidase ) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC 50 s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts.

Application

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Product Information

• Catalog No.: HY-151498A
• CAS No.: 2409964-40-3
• Molecular Formula: C10H13ClFNO2S
• Molecular Weight: 265.73
• Purity: 99.71%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source