Sabutoclax

Sabutoclax
  • CAS No.:1228108-65-3
  • Grade:98.03%
  • Formula:C42H40N2O8
  • M.W.:700.78
  • Solvent:≥ 2.75 mg/mL (3.92 mM); Clear solution

Overview

Sabutoclax is a potent and effective Bcl-2 Family ( Bcl-2 , Bcl-XL , Mcl-1 , Bfl-1 ) inhibitor with IC 50 s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively. Sabutoclax increases Bax , Bim , PUMA and survivin expression.

Application

Products | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

  • Catalog No.: HY-15191
  • CAS No.: 1228108-65-3
  • Molecular Formula: C42H40N2O8
  • Molecular Weight: 700.78
  • Purity: 98.03%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.75 mg/mL (3.92 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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