ATR-IN-20

Overview

ATR-IN-20 is a potent ATR ( ATM/ATR ) inhibitor with an IC 50 of 3 nM. ATR-IN-20 possess an inhibitory effect on mTOR ( IC 50 of 18 nM) while displaying good selectivity against PI3Kα (100 nM), ATM (100 nM), and DNA-PK (662 nM). ATR-IN-20 exhibits excellent pharmacokinetic profile (F = 30%), and has anticancer effects.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ATM/ATR | Products > Signaling Pathways > mTOR

Product Information

• Catalog No.: HY-151915
• CAS No.: 3012609-63-8
• Molecular Formula: C29H31N5O4S
• Molecular Weight: 545.65
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source