NADPH oxidase-IN-1

Overview

NADPH oxidase-IN-1 is an orally active NADPH oxidase ( Nox ) inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier (BBB), inhibits Nox2 and Nox4 with IC 50 s of 1.9 μM and 2.47 μM, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy.

Application

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Product Information

• Catalog No.: HY-152026
• CAS No.: 2762405-17-2
• Molecular Formula: C20H27N3O2S
• Molecular Weight: 373.51
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source