Topoisomerase IIα-IN-5 is a topoisomerase II ( topo II ) α catalytic inhibitor. Topoisomerase IIα-IN-5 intercalates into DNA and binds to the DNA minor groove. Topoisomerase IIα-IN-5 exhibits better efficacy and less genotoxicity than Etoposide ( HY-13629 ).
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Others | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Apoptosis
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