WYE-687 dihydrochloride

Overview

WYE-687 dihydrochloride is an ATP-competitive mTOR inhibitor with an IC 50 of 7 nM. WYE-687 dihydrochloride concurrently inhibits activation of mTORC1 and mTORC2 . WYE-687 also inhibits PI3Kα and PI3Kγ with IC 50 s of 81 nM and 3.11 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-15271A
• CAS No.: 1702364-87-1
• Molecular Formula: C28H34Cl2N8O3
• Molecular Weight: 601.53
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source