BMY 14802 is a sigma-1 receptor ( σ1R ) antagonist, as well as an agonist at serotonin (5-HT) 1A and adrenergic alpha-1 receptors . BMY 14802 inhibits abnormal involuntary movement (AIM) in rat Parkinson's disease (PD) model, with down-regulating the expression of AIM.
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