PI3Kγ inhibitor 7 (compound 2) is a potent and orally active PI3Kγ inhibitor with IC 50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα , PI3Kβ , PI3Kγ , PI3Kδ , respectively. PI3Kγ inhibitor 7 shows antitumor activity. PI3Kγ inhibitor 7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K
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