KB-R7943 mesylate

Overview

KB-R7943 mesylate is a widely used inhibitor of the reverse Na + /Ca 2+ exchanger (NCX rev ) with IC 50 of 5.7±2.1 μM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Na+/Ca2+ Exchanger | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-15415
• CAS No.: 182004-65-5
• Molecular Formula: C17H21N3O6S2
• Molecular Weight: 427.50
• Purity: 99.16%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.85 mM); Clear solution
• Availability: In-stock

Source

Original product source