mTOR inhibitor-11 (Compound 9) is a brain-penetrant mTOR inhibitor ( IC 50 : 21 nM for pS6). mTOR inhibitor-11 also inhibits pCHK1 and PDE4D with IC 50 s of 17.2 and 17.0 μM. mTOR inhibitor-11 can be used for research of CNS disease.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mTOR
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