Pruvonertinib

Overview

YK-029A is an orally active inhibitor of mutant EGFR ，targeting to both the T790M mutations ( EGFR T790M ) and exon 20 insertion of EGFR (EGFRex20ins). YK-029A exhibits significant antitumor activity，and results tumor regression in EGFRex20ins-driven PDX models.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-155537
• CAS No.: 2064269-82-3
• Molecular Formula: C27H32N8O2
• Molecular Weight: 500.60
• Purity: 99.50%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (4.99 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source