(-)-5-HT2C agonist-3 (compound (-)-19) is a 5-HT 2C selective agonist with G q signaling preference, with EC 50 values for 5-HT 2 receptors of 5-HT 2C : 103 nM; 5-HT 2B : 570 nM; 5-HT 2A : 72 nM. (-)-5-HT2C agonist-3 can be used in antipsychotic research.
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