ICMT-IN-48

Overview

ICMT-IN-48 (compound 1) is an ICMT inhibitor that is competitive (Km=13 μM) for the prenylated methyl acceptor, the first substrate of ICMT . ICMT-IN-48 inhibits ICMT activity with IC 50 s affected by the concentration of the second substrate S-adenosylmethinine (SAM), and the IC 50 s are 3.5 μM (1×Km SAM) and 2.3 μM (10×Km SAM), respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ICMT

Product Information

• Catalog No.: HY-157116
• CAS No.: 337486-54-1
• Molecular Formula: C30H37NO5
• Molecular Weight: 491.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source