AChE/BChE-IN-16 (compound C7) is a potent cholinesterase (ChE) inhibitor with IC 50 s of 30 nM and 48 nM for human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE) , respectively. AChE/BChE-IN-16 exhibits a remarkable capacity to safeguard PC12 cells against H 2 O 2 -induced apoptosis and effectively suppresses the production of reactive oxygen species (ROS) .
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