NDT-19795

Overview

NDT-19795 is an effective inhibitor of the NLRP3 inflammasome with an IC 50 value of 66 nM in the PBMC method and 4.7 μM in the WB method. NDT-19795 is a carboxylic acid-active substance that can be converted from NT-0796 ( HY-156438 ) within cells. NDT-19795 can be used for the studies of inflammation and neurological diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Depression | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-158024
• CAS No.: 2272917-12-9
• Molecular Formula: C20H21N3O4
• Molecular Weight: 367.40
• Purity: 99.16%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.80 mM); Clear solution
• Availability: In-stock

Source

Original product source