FIIN-1

FIIN-1
  • CAS No.:1256152-35-8
  • Grade:99.04%
  • Formula:C32H39Cl2N7O4
  • M.W.:656.60
  • Solvent:≥ 2.08 mg/mL (3.17 mM); Clear solution

Overview

FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with K d s of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC 50 s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively.

Application

Products | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FGFR

Product Information

  • Catalog No.: HY-15813
  • CAS No.: 1256152-35-8
  • Molecular Formula: C32H39Cl2N7O4
  • Molecular Weight: 656.60
  • Purity: 99.04%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (3.17 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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