LDN-212854 is a bone morphogenetic protein ( BMP ) inhibitor that potently inhibits ALK2 ( IC 50 : 1.3 nM). LDN-212854 also inhibits ALK1 (IC 50 : 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC).
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