AZ683

AZ683
  • CAS No.:953798-95-3
  • Grade:98.57%
  • Formula:C23H25F2N5O2
  • M.W.:441.47
  • Solvent:≥ 5 mg/mL (11.33 mM); Clear solution

Overview

AZ683 is a potent and selective 3-amido-4-anilinoquinoline CSF1R inhibitor. AZ683 has high affinity for CSF1R ( K i =8 nM; IC 50 =6 nM). AZ683 has good oral bioavailability. [ 11 C]AZ683 can be used as a positron emission tomography (PET) radiotracer for colony stimulating factor 1 receptor (CSF1R).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > c-Fms

Product Information

  • Catalog No.: HY-159108
  • CAS No.: 953798-95-3
  • Molecular Formula: C23H25F2N5O2
  • Molecular Weight: 441.47
  • Purity: 98.57%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (11.33 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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