CD 10899 is a hydroxylated metabolite of Volasertib ( HY-12137 ). CD 10899 is pharmacologically active against Polo-like kinase 1 ( PLK1 ) ( IC 50 : 6 nM). Volasertib is an orally active, highly potent and ATP-competitive PLK1 inhibitor . CD 10899 can be used for research of cancer .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Polo-like Kinase (PLK)
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