2,6-Didehydropeperomin B

Overview

DHP-B is an Ecolignan-type compound and covalent, selective CPT1A inhibitor with a K d of 1.62 μM. DHP-B can be isolated from the plant Peperomia dindygulensis . DHP-B covalently binds to Cys96 of CPT1A, blocks FAO , and disrupts the mitochondrial CPT1A-VDAC1 interaction. DHP-B triggers Apoptosis . DHP-B exhibits anti-CRC activity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carnitine Palmitoyltransferase (CPT) | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-161027
• CAS No.: 1186292-00-1
• Molecular Formula: C23H24O8
• Molecular Weight: 428.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source