Cyclin K degrader 1

Overview

Cyclin K degrader 1 (compound 40) is an AT7519 ( HY-50940 ) based Cyclin K degrader with DC 50 of 21 nM. Cyclin K degrader 1 has an affinity for cyclin K that is ~500-fold higher than its affinity for CDK12 .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-161168
• CAS No.: 3055008-98-2
• Molecular Formula: C23H17Cl2N5O2
• Molecular Weight: 466.32
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.36 mM); Clear solution
• Availability: In-stock

Source

Original product source