VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases . VD4162 can significantly improve potency for all four target enzymes TMPRSS2 ( IC 50 = 3.7 nM), HGFA( IC 50 = 3.3 nM), matriptase ( IC 50 = 2.9 nM), and hepsin ( IC 50 = 0.54 nM). VD4162 can be used for the research of cancer .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ser/Thr Protease
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