hCAI/II-IN-8 (Compound 8) is a hydrazide derivative based on 4-hydroxybenzaldehyde. hCAI/II-IN-8 primarily targets human carbonic anhydrase isomerase I ( hCA I ) and II ( hCA II ) for inhibition ( IC 50 = 21.35 ± 0.39 nM (hCA I); 7.12 ± 0.12 nM (hCA II)). hCAI/II-IN-8 inhibits AChE and BChE as well( IC 50 = 46.27 ±0.75 nM ( AChE ); 43.38 ± 0.83 nM ( BChE )). ..
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Carbonic Anhydrase | Products > Signaling Pathways > Cholinesterase (ChE)
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