TLR8 agonist 9

Overview

TLR8 agonist 9 (Compound II-77) is an agonist for Toll-like receptor 8 ( TLR8 ) with EC 50 of 0.25-1 μM. TLR8 agonist 9 is stable in human and murine plasma, induces secretion of cytokines TNFα, with EC 50 <1 μM. TLR8 agonist 9 exhibits antitumor activity in MC38-HER2 xenograft mouse model with a tumor growth inhibition (TGI) rate of 97%.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

• Catalog No.: HY-161631
• CAS No.: 3034750-61-0
• Molecular Formula: C38H43N7O8
• Molecular Weight: 725.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source