Sitneprotafib

Overview

Sitneprotafib (JAB-3312) is an orally effective anticancer phosphatase SHP2 inhibitor ( IC 50 : 1.9 nM) with anti-cancer activity. Sitneprotafib has good tolerability and significantly induced tumor regression in a KYSE-520 mouse xenograft model.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2

Product Information

• Catalog No.: HY-161952
• CAS No.: 2245082-05-5
• Molecular Formula: C21H22ClN7S
• Molecular Weight: 439.96
• Purity: 99.64%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.68 mM); Clear solution
• Availability: In-stock

Source

Original product source