MSA-2-Pt

Overview

MSA-2 -Pt, platinum salt-modified MSA-2 ( HY-136927 ), is a STING agonist. MSA-2 -Pt inducing cell death by platinum and activating the STING pathway by MSA-2 . MSA-2 -Pt direct activates STING pathway, induces phosphorylation of TBK1 , IRF3 , and NF-κB p65 . MSA-2 -Pt enhances tumor infiltration of CD4 + and CD8 + T cells, and induces tumor cell death and apoptosis in mouse colon carcinoma and melanoma models.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > STING | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > IKK | Products > Signaling Pathways > IFNAR | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-162133
• CAS No.: 3028778-96-0
• Molecular Formula: C28H32N2O10PtS2
• Molecular Weight: 815.78
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source