GGTI-2417

Overview

GGTI-2417 is a potent and selective inhibitor of GGTase I . GGTI-2417 inhibits the Cdk2-mediated phosphorylation of p27 Kip1 at Thr187 and accumulates p27 Kip1 in the nucleus. GGTI-2417 also induces breast cancer cell apoptosis .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ROS Kinase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-16230
• CAS No.: 501010-05-5
• Molecular Formula: C24H33N5O4
• Molecular Weight: 455.55
• Purity: 98.97%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.49 mM); Clear solution
• Availability: In-stock

Source

Original product source