PARP7/HDACs-IN-1 (compound 9l) is a dual-target inhibitor targeting PARP7 / HDAC with anti-tumor activity. PARP7/HDACs-IN-1 inhibits different subtypes of PARPs and HDACs with IC 50 s of 83.3 nM ( PARP1 ), 3.1 nM ( PARP7 ), 35 nM ( HDAC1 ), 30.3 nM ( HDAC2 ), 35.4 nM ( HDAC3 ), and 6.4 nM respectively. ( HDAC6 ). br/.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > PARP
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