BIO-7488

Overview

BIO-7488 is an orally active, selective and blood-brain barrier permeable IRAK4 inhibitor, with an IC 50 value of 0.5 nM. BIO-7488 inhibits the production of pro-inflammatory cytokines (IL-1β, TNFα, IL-6 ) and demonstrates anti-inflammatory effects in both LPS ( HY-D1056 ) and distal hypoxic-middle cerebral artery occlusion (DH-MCAO) ischemic stroke model. BIO-7488 can be used for the study of neuroinflammatory-related diseases, particularly ischemic stroke.

Application

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Product Information

• Catalog No.: HY-162359
• CAS No.: 2573211-25-1
• Molecular Formula: C23H25N7O3
• Molecular Weight: 447.49
• Purity: 99.44%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source