EGFR-IN-109 (compound 4) is an EGFR inhibitor , with the IC 50 values of 25.8 and 182.3 nM for EGFR WT and EGFR T790M , respectively. EGFR-IN-109 arrests the cancer cells’ growth at the G2/M phase and induces both early and late apoptosis . EGFR-IN-109 can be used in cancer research.
Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Bcl-2 Family
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