UNC8969 (compound 43) is a MERTK/AXL dual inhibitor with IC 50 s of 1.1±0.8 nM for MERTK and 5.3 ± 2.7 nM for AXL . UNC8969 also exerts a T 1/2 of 7.3 h with 5 mg/kg i.v. in mice.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > TAM Receptor
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