FAK inhibitor 7 is a type of FAK inhibitor with an IC 50 value of 3.58 nM. FAK inhibitor 7 can inhibit the downstream signaling cascades of FAK (like Src and AKT ), causing ovarian cancer cells to stall in the G0/G1 phase and induce cytotoxic autophagy . FAK inhibitor 7 can also suppress tumor metastasis and growth in ovarian cancer mice.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > FAK | Products > Signaling Pathways > Src | Products > Signaling Pathways > Akt | Products > Signaling Pathways > Autophagy
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