pan-KRAS-IN-18

pan-KRAS-IN-18
  • CAS No.:2937327-83-6
  • Grade:99.93%
  • Formula:C22H26N8OS
  • M.W.:450.56
  • Solvent:≥ 5 mg/mL (11.10 mM); Clear solution

Overview

pan-KRAS-IN-18 is a pan KRAS inhibitor that inhibits KRAS WT and KRAS G12V with IC 50 s of 29 and 9 nM, respectively. pan-KRAS-IN-18 exhibits antiproliferative activity in KRAS-mutant cell lines. pan-KRAS-IN-18 can be used for lung cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Ras

Product Information

  • Catalog No.: HY-162960
  • CAS No.: 2937327-83-6
  • Molecular Formula: C22H26N8OS
  • Molecular Weight: 450.56
  • Purity: 99.93%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (11.10 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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