W6134

Overview

W6134 is highly potent and selective RORγ covalent inhibitor with an IC 50 of 0.21 μM. W6134 exhibits excellent selectivity for RORγ over RORα , RXRγ , and ERRγ . W6134 significantly inhibits RORγ transcriptional activity W6134 inhibits the proliferation and colony formation and induces apoptosis in castration-resistant prostate cancer cells (CRPC). W6134 can be used for the research of castration-resistant prostate cancers (CRPC).

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ROR | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-163192
• CAS No.: 2983540-55-0
• Molecular Formula: C25H23ClN2O4S
• Molecular Weight: 482.98
• Purity: 99.90%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source