sEH/HDAC6-IN-1 (compound M9) is a selective, orally active dual inhibitor for sEH and HDAC6 , with IC 50 s of 2 nM, 0.72 nM and 5 nM, for human sEH, murine sEH and HDAC6 , respectively. sEH/HDAC6-IN-1 reveals analgesic and anti-inflammatory effects.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Epoxide Hydrolase | Products > Signaling Pathways > HDAC
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