NCA029

Overview

NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC 50 of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death.

Application

Products | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ClpP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-163319
• CAS No.: 3032667-94-7
• Molecular Formula: C22H20F3N3O
• Molecular Weight: 399.41
• Purity: 98.24%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.26 mM); Clear solution
• Availability: In-stock

Source

Original product source