HDAC6-IN-48

Overview

HDAC6-IN-48 (compound 5i) is a potent and selective HDAC6 inhibitor with IC 50 values of 5.16, 396.72, 638.08 nM for HDAC6 , HDAC3 , HDAC1 , respectively. HDAC6-IN-48 induces apoptosis and cell cycle arrest at G0/G1 phase. HDAC6-IN-48 increases the protein expression of acetylated α-tubulin.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-163894
• CAS No.: 3052111-12-0
• Molecular Formula: C24H21N3O4
• Molecular Weight: 415.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source