EGFR T790M/L858R-IN-8 (Compound 9) is a selective EGFR T790M/L858R mutant kinase inhibitor with a IC 50 of 56.8 μM, and it shows no inhibitory activity against wild-type EGFR . EGFR T790M/L858R-IN-8 can be used for the research of non-small cell lung cancer .
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