U-78517 dihydrochloride, a Trolox ( HY-101445 ) analog, is a potent antioxidant. U-78517 dihydrochloride inhibits DCVC ( HY-19717 )-induced lipid peroxidation, scavenges DPPH , oxygen- and nitrogen-based free radicals. U-78517 dihydrochloride attenuates hypoxic injury in iaolated cardiac myocytes. U-78517 dihydrochloride can be used for the research of hypoxic injury, cerebral ischemia, and cardiovascular disease .
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