Tegafur -gimeracil-oteracil potassium (S-1; TS-1) is an orally active anticancer agent composed of Tegafur ( HY-17400 ), Gimeracil ( HY-17469 ), and Oteracil potassium ( HY-17511 ). Tegafur -gimeracil-oteracil potassium inhibits the proliferation, migration and invasion of endometrial cancer cells and induces apoptosis by blocking the PI3K / AKT / mTOR signaling pathway. Tegafur -gimeracil-oteracil potassium can be used in research related to endometrial cancer and gastric cancer with peritoneal metastasis.
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