CP-470711 is an orally active and potent and selective sorbitol dehydrogenase ( SDH ) inhibitor with an IC 50 =10 nM for human SDH and IC 50 =17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Aldehyde Dehydrogenase (ALDH)
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