Clofarabine -5'-triphosphate is the metabolite of Clofarabine ( HY-A0005 ) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine -5'-triphosphate exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis
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