(E)-Dothiepin hydrochloride

(E)-Dothiepin hydrochloride
  • CAS No.:25627-36-5
  • Grade:99.98%
  • Formula:C19H22ClNS
  • M.W.:331.90

Overview

(E)-Dothiepin ((E)-Dosulepin;(E)-Dothep) hydrochloride is an antidepressant agent with sedative/anxiolytic activity. (E)-Dothiepin hydrochloride is an inhibitor preferring of noradrenaline uptake than serotonin uptake. (E)-Dothiepin hydrochloride facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. (E)-Dothiepin hydrochloride is also an antagonist of histamine H1-receptor without cardiotoxicity. (E)-Dothiepin hydrochloride exhibits significant analgesic activity in psychogenic facial pain,idiopathic fibromyalgia syndrome or rheumatoid arthritis.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Histamine Receptor

Product Information

  • Catalog No.: HY-165378
  • CAS No.: 25627-36-5
  • Molecular Formula: C19H22ClNS
  • Molecular Weight: 331.90
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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