TDPAM02

Overview

TDPAM02 is a positive allosteric modulator of AMPA receptor GluA2 . TDPAM02 can specifically bind to the ligand-binding domain (LBD) of GluA2 and shows an IC 50 of 1.4 nM for the GluA2 flop subtype. TDPAM02 can stabilize the activated conformation of GluA2 receptors, delay the receptor deactivation or desensitization process, maintaining the rapid excitatory synaptic transmission in the central nervous system.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-165475
• CAS No.: 2231101-34-9
• Molecular Formula: C22H26N4O4S2
• Molecular Weight: 474.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source