Mofegiline hydrochloride (MDL72974A) is an orally active and selective enzyme-activated irreversible inhibitor of MAO-B , with marked selectivity on the MAO-B over MAO-A with IC 50 s of 3.6 nM ( MAO-B ) and 680 nM ( MAO-A ), respectively. Mofegiline hydrochloride is also an inhibitor of semicarbazide-sensitive amine oxidase ( SSAO ).
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