Verosudil

Overview

Verosudil (AR-12286) is a ROCK inhibitor. Verosudil has equal inhibitory activity against ROCK1 and ROCK2 ( K i : 2 nM). Verosudil is less selective for PKA , PKCT, MRCKA, and CAM2A (K i : 69 nM, 9322 nM, 28 nM, 5855 nM, respectively). Verosudil increases trabecular outflow capacity to reduce intraocular pressure. Verosudil is useful in the study of glaucoma and ocular hypertension.

Application

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Product Information

• Catalog No.: HY-16758
• CAS No.: 1414854-42-4
• Molecular Formula: C17H17N3O2S
• Molecular Weight: 327.40
• Purity: 98.22%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.67 mg/mL (5.10 mM); Clear solution
• Availability: In-stock

Source

Original product source