ASP-2205 is a 5-HT 2C receptor agonist (human 5-HT 2C receptor, EC 50 =0.85 nM; rat 5-HT 2C receptor, EC 50 =2.5 nM). ASP-2205 enhances the pudendal nerve-mediated urethral closure reflex through the 5-HT 2C receptor, thereby preventing urinary incontinence.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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