MLS-0053105

Overview

MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC 50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W , Bcl-2 , and Bcl-XL and no activity against Bcl-B and Mcl-1 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-167881
• CAS No.: 370572-36-4
• Molecular Formula: C15H14Cl3N3O2
• Molecular Weight: 374.65
• Purity: 98.89%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source